What would I lose when going S60 -> Belle?

So I'm probably as intrigued as anyone is by the Pureview and since it looks to be a while before it surfaces on WP7/8, I'm mulling over potentially replacing the E5-00, my main 'talk backup' (due to the battery life mainly) with an 808.The keyboard of the E5 is to me a little sucky (or maybe my thumbs are just too big) and the move to a Symbian touchscreen probably wouldn't bother me.

The question is, what do I lose on a Belle device if anything, compared to S60 on an E5-00? Exchange sync is pretty much a must, and I need Skype and Spotify on it as well.