One of the complaints I have read over-and-over is that Windows 8 does not work well with a traditional mouse and keyboard. I have used it with both a touchpad and a mouse and keyboard, and do not agree with that sentiment. I think it works fine, but (honestly) not great.
But, that is the point. Windows 8 is a touch first OS. It was not built to work with the mouse first (gasp!). I know this is a lot to take in, but bear with me. We have only seen two disruptive shifts in user input in the past two decades: the mouse and touch. Just as it seems almost ridiculous to use a computer without a mouse today. After October, it is going to seem just as crazy to use a computer without touch. Sure, there will be some laggards. I know a few developers that swear by VI and code completely without a mouse. But, that is not the point.
The point is that we are at a generational shift in computing. And, Windows 8 and Microsoft are leading the way. Embrace it. Yes, there will be pundits and many who are not ready to change. I get that. But, I personally think this is the right move both from a product standpoint and technological standpoint. And, I look forward to the first fully functional, touch-first OS.