Has anybody here set up an "Apple-centric" home entertainment system?

Since my wife and I mostly own Apple devices and since all our music collection is on iTunes, I am thinking of going with a completely 'Apple-centric' home entertainment system for our new home. I am looking for the most elegant solution to wirelessly stream music & video from any device to any room in the house.

Anybody have any experience setting up such a system with Apple TV, iTunes library on a NAS storage device, AirPlay enabled wireless music system throughout the house (Bose Soundlink / Sonos / Samsung Shape)?

I'd appreciate any thoughts/suggestions/tips you may have.